YOUTH LEAGUE – CAMPIONI NAZIONALI
PRIMO TURNO
Gare di Ritorno
| Midtjylland – Rosenborg | 10 – 1 | (4 – 2) |
| AZ Alkmaar – Gabala | 7 – 0 | (4 – 0) |
FC Minsk – Daugavpils Hajduk Split – Shkëndija |
2 – 0 | 4 – 0) |
| Genk – Köln | 3 – 1 | (4 – 2) |
| Akademia e Futibollit – Septemvri Sofia | 4 – 0 | (0 – 3) |
| Trabzonspor – Zvijezda 09 | 2 – 0 | (1 – 0) |
| Kairat Almaty – APOEL | 1 – 0 | (1 – 1) |
| Sparta Praha – MTK Budapest | 3 – 3 | (1 – 3) |
| Angers – Csikszereda | 3 – 0 | (2 – 0) |
| Žilina – PAOK | 2 – 0 | (5 – 1) |
| Crvena zvezda – Saint Patrick’s Athletic | 2 – 0 | (2 – 1) |
| Maccabi Haifa – Žalgiris Vilnius | 2 – 0 | (3 – 0) |
| Hammarby – Rangers | 1 – 2 | (0 – 3) |
| Empoli – Domžale | 1 – 1 | (2 – 1) |
| Deportivo La Coruña – Pogoń Szczecin | 4 – 0 | (0 – 3) |
| Hajduk Split – Shkendija | 3 – 1 | (5 – 1) |
In neretto le squadre classificate al 2° turno.
Le Gare del 2° turno si disputeranno il 3 ed il 24 novembre 2021
